Basic information Safety Supplier Related

(+/-)9-HODE

Basic information Safety Supplier Related

(+/-)9-HODE Basic information

Product Name:
(+/-)9-HODE
Synonyms:
  • (+/-)9-HODE
  • (+/-)-9-HYDROXY-10E,12Z-OCTADECADIENOIC ACID
  • (+/-)-9-HYDROXYOCTADECA-10E,12Z,DIENOIC ACID
  • (10E,12Z)-9-Hydroxy-10,12-octadecadienoic acid
  • 9-Hydroxyoctadecadienoic acid
  • 9-Hydroxy-trans-10,cis-12 octadecadienoic acid
  • NPDSHTNEKLQQIJ-ZJHFMPGASA-N
  • (±)-9-Hydroxyoctadeca-10E,12Z-dienoic acid (9-HODE)
CAS:
98524-19-7
MF:
C18H32O3
MW:
296.44
Mol File:
98524-19-7.mol
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(+/-)9-HODE Chemical Properties

Boiling point:
416.1±33.0 °C(Predicted)
Density 
0.970±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form 
Clear to light-yellow liquid.
pka
4.78±0.10(Predicted)
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(+/-)9-HODE Usage And Synthesis

Description

(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs and HODEs.

Uses

(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs and HODEs.

Uses

(+/-)9-HODE is a distinct product of non-enzymatic linoleic acid oxidation.Also, it is one of the component in rice koji extract (RKE), which activates peroxisome proliferator-activated receptor alpha (PPARα).It is derived from Methyl Linoleate (M265190), which is a common methyl ester produced from soybean or canola oil and methanol. Methyl Linoleate is classified as a biodiesel due to its long methyl chain and is used as a fuel in standard diesel engines.

Definition

ChEBI: 9-HODE is a HODE that consists of (10E,12Z)-octadecadienoic acid with the hydroxy substituent located at position 9. It has a role as a plant metabolite, a human metabolite and a mouse metabolite. It is a conjugate acid of a 9-HODE(1-).

(+/-)9-HODESupplier

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