(4R)-4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Chemical Properties

Boiling point:

207 °C(lit.)

Density 

1.045 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4390(lit.)

Flash point:

224 °F

pka

14.80±0.10(Predicted)

form 

clear liquid

color 

Colorless to Almost colorless

InChIKey

YYEZYENJAMOWHW-ZCFIWIBFSA-N

CAS DataBase Reference

70005-89-9

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29329990

MSDS

• Language:English Provider:SigmaAldrich

(4R)-4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Usage And Synthesis

Uses

(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane can be used:

• To introduce a chiral center selectively in the carbon chain C10 during the total synthesis of protectin D1.
• As a starting material in the total synthesis of an anti-diabetic molecule cytopiloyne.
• As a starting material in the preparation of 4-¹⁵N-amino-2-butane-1,2-diol, which is used to synthesize ¹⁵N-labeled oligodeoxynucleotides.

(4R)-4-(2-HYDROXYETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE(70005-89-9)Related Product Information

• Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside
• fluocinolone16,17-acetonide
• 2',3'-O-Isopropylideneadenosine
• (+)-5,6-O-Isopropylidene-L-ascorbic acid
• 2′,3′-O-Isopropylideneuridine
• Methyl-2,3-O-isopropylidene-D-ribofuranoside
• DIACETONE-D-GLUCOSE
• 2',3'-O-Isopropylideneinosine
• 5-O-CARBOMETHOXY-1,2-O-ISO-PROPYLIDENE-3-O-(P-TOLYL-SULFONYL)-ALPHA-D-XYLOFURANOSE
• 6-Deoxy-1,2:3,4-di-O-isopropylidene-6-iodo-ALPHA-D-galactopyranose
• 5-O-CARBOMETHOXY-1,2-O-ISOPROPYLIDENE-D-XYLOFURANOSE
• 1,6-ANHYDRO-3,4-O-ISOPROPYLIDENE-2-TOSYL-B-D-GALACTOPYRANOSE
• 2',3'-O-ISOPROPYLIDENE-5'-TRITYLINOSINE
• 5'-ACETYL-2',3'-ISOPROPYLIDENEADENOSINE
• 6-O-ACETYL-1,2:3,4-DI-O-ISOPROPYLIDENE-ALPHA-D-GALACTOPYRANOSE
• 1,2:3,5-DI-O-ISOPROPYLIDENE-ALPHA-D-APIOSE
• 1 2-O-ISOPROPYLIDENE-3-O-METHYL-ALPHA-D&
• 1,2:5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-RIBO-3-HEXULOFURANOSE