Basic information Safety Supplier Related

Oseltamivir EP Impurity E HCl

Basic information Safety Supplier Related

Oseltamivir EP Impurity E HCl Basic information

Product Name:
Oseltamivir EP Impurity E HCl
Synonyms:
  • Oseltamivir Methyl Ester HCl
  • methyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
  • Oseltamivir EP Impurity E HCl
  • methyl(3R,4R,5S)-4-acetamido-5-amino-3-(1-ethyl-propxy)cyclohex-1-ene-1-carboxlate
  • (3R,4R,5S)-methyl 4-acetamido-5-amino
  • Oseltamivir EP Impurity E:Oseltamivir Impurity E
  • Oseltamivir Impurity(Oseltamivir EP Impurity E)
  • Oseltamivir EP Impuruty E
CAS:
208720-78-9
MF:
C15H27ClN2O4
MW:
334.84
Mol File:
208720-78-9.mol
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Oseltamivir EP Impurity E HCl Chemical Properties

InChI
InChI=1/C15H26N2O4.ClH/c1-5-11(6-2)21-13-8-10(15(19)20-4)7-12(16)14(13)17-9(3)18;/h8,11-14H,5-7,16H2,1-4H3,(H,17,18);1H/t12-,13+,14+;/s3
InChIKey
VXUUEBWFJPUQGY-XGEKKEJANA-N
SMILES
O([C@@H]1C=C(C(=O)OC)C[C@H](N)[C@H]1NC(=O)C)C(CC)CC.Cl |&1:1,9,11,r|
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Oseltamivir EP Impurity E HCl Usage And Synthesis

Uses

Oseltamivir acid methyl ester hydrochloride is a precursor form of the neuraminidase inhibitor and antiviral oseltamivir acid. Oseltamivir acid methyl ester hydrochloride is converted to oseltamivir acid by carboxylesterase 1 (CES1)[1].

References

[1] Mai Shimizu, et al. Systematic Approach for Screening of Prodrugs: Evaluation Using Oseltamivir Analogues as Models. J Pharm Sci. 2021 Feb;110(2):925-934. DOI:10.1016/j.xphs.2020.10.018

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