S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Basic information
- Product Name:
- S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
- Synonyms:
-
- (6S)-6-(diMethylaMino)-4,4-diphenylheptan-3-one
- S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
- (s)-6-(dimethylamino)-4,4-diphenyl-3-heptanone
- 4-diphenyl-6-(dimethylamino)-(s)-3-heptanon
- 6s-methadone
- d-6-(dimethylamino)-4,4-diphenyl-3-heptanone
- dextromethadone
- d-methadone
- CAS:
- 5653-80-5
- MF:
- C21H27NO
- MW:
- 309.45
- Mol File:
- 5653-80-5.mol
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S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Chemical Properties
- Melting point:
- 100.5°C
- Boiling point:
- 449.71°C (rough estimate)
- Density
- 1.0350 (rough estimate)
- refractive index
- 1.5614 (estimate)
- solubility
- H2O: soluble
- form
- solid
- pka
- 9.05±0.50(Predicted)
- color
- white
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-42/43
- Safety Statements
- 22-26-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- MJ6000000
- Toxicity
- LD50 oral in mouse: 252mg/kg
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S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Usage And Synthesis
Uses
Dextromethadone-D3 is an impurity of Dextromethadone (CAS #: 5653-80-5). Dextromethadone is used in therapy for treating or preventing depression or other mood diseases.
Definition
ChEBI: Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.