N-HydroxysucciniMidyl Pyrenebutanoate Chemical Properties

Melting point:

132-136 °C(lit.)

storage temp. 

room temp

solubility 

Soluble in chloroform, N,N- dimethylformamide, dimethyl sulfoxide, methanol

form 

A solid

color 

Yellow solid

Appearance

off-white solid

λmax

340nm, 325nm (MeOH)

Major Application

Carbon nanotubes (single-wall carbon nanotubes (SWCNT) and multi-wall carbon nanotubes (MWCNTs)); cellulose materials for bulky paper sheets; graphene-based polymer nanocomposites materials/films; photonic materials;photovoltaic devices; polyaniline systems;poly(dimethylsiloxane) (PDMS) oligomers;poly(propylene imine) dendrimers; thin-films

Biological Applications

Characterizing cyclodextrin-based polyrotaxanes; detecting nucleic acids,polyamines;immobilizing proteins;probing lysozyme in human serum; as a substrate for measuring polymerases activity, recombinases activity, topoisomerases activity

InChI

InChI=1S/C24H19NO4/c26-20-13-14-21(27)25(20)29-22(28)6-2-3-15-7-8-18-10-9-16-4-1-5-17-11-12-19(15)24(18)23(16)17/h1,4-5,7-12H,2-3,6,13-14H2

InChIKey

YBNMDCCMCLUHBL-UHFFFAOYSA-N

SMILES

C1(CCCC(ON2C(=O)CCC2=O)=O)=C2C3=C4C(C=C2)=CC=CC4=CC=C3C=C1

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2928.00.5000

N-HydroxysucciniMidyl Pyrenebutanoate Usage And Synthesis

Description

Pyrene is a polyaromatic hydrocarbon which exhibits fluorescence in blue range of the spectrum. When two pyrene residues are closely spaced, excimer fluorescence is observed at longer wavelength. Therefore, pyrene is useful as a proximity label.

Pyrene exhibits affinity to graphite, and can be used as an anchor group for graphite. This reagent can be conjugated with biomolecules for their subsequent immobilization on graphite surfaces.

This NHS ester allows to label biomolecules with amino groups, such as proteins, peptides, amino-DNA and other molecules.

Pyrene is also a FRET donor for perylene.

Uses

N-Hydroxysuccinimidyl Pyrenebutanoate is a novel fluorescent monomer used as new material for protein conjugation. Dyes and metabolites.

General Description

1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is an aromatic chemical, which is also known as PBSE. It is a yellow solid, that is soluble in chloroform, N,N dimethyl formamide, dimethyl sulfoxide and methanol. It is used in detecting nucleic acids, characterizing cyclodextrin based polyrotaxanes, immobilizing proteins etc.

Abs/Em Maxima

343; 326; 313; 276; 265; 242; 234/377; 397 nm

N-HydroxysucciniMidyl Pyrenebutanoate(114932-60-4)Related Product Information

• SUCCINIMIDYL 4-FORMYLBENZOATE
• N-SUCCINIMIDYL 4-NITROPHENYLACETATE
• Methylparaben
• 1-N-BUTYLPYRENE
• Sulfo-succinimidyl-(1-pyrenyl)butyrate
• N-HydroxysucciniMidyl Pyrenebutanoate
• 1-N-PROPYLPYRENE
• 1-PYRENEBUTYRIC ACID
• 4-(2-Naphthyl)butanoic acid
• 3-ETHYLPHENANTHRENE
• 1-ETHYLPYRENE
• 1-METHYLPYRENE
• 1-PYRENEBUTANOL