Tanomastat
Tanomastat Basic information
- Product Name:
- Tanomastat
- Synonyms:
-
- TANOMASTAT
- BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid
- (S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid
- (S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid
- D03802
- Tanomastat (usan/inn)
- (S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
- [1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-
- CAS:
- 179545-77-8
- MF:
- C23H19ClO3S
- MW:
- 410.91
- Product Categories:
-
- Chiral Reagents
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Sulfur & Selenium Compounds
- Mol File:
- 179545-77-8.mol
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Tanomastat Chemical Properties
- Melting point:
- 110-110.5°C
- Boiling point:
- 620.1±55.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 4.01±0.23(Predicted)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 179545-77-8
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Tanomastat Usage And Synthesis
Chemical Properties
White Solid
Uses
A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor. Optical Rotation +82?(C 1.5 acetone)
Uses
Tanomastat is an orally available, non-peptidic inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, and MMP-9 (Kis = 11, 143, and 301 nM, respectively). It is active in various animal models of tumor metastasis and has been used in a phase III clinical trial in pancreatic, SCLC, NSCLC, and ovarian cancer patients.
Uses
A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).
Definition
ChEBI: Tanomastat is an organochlorine compound and a member of biphenyls.
TanomastatSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
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