ACAD9 antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

The mitochondrial flavoenzymes acyl-CoA dehydrogenases catalyze the α,β dehydrogenation of acyl-CoA esters. One of these enzymes, ACAD9, is essential for assembly of oxidative phosphorylation complex I. Studies have shown that ACAD9 gene mutations cause Complex I deficiency.

References

[1] He, M. et al. (2007) Am J Hum Genet 81, 87-103.
[2] Nouws, J. et al. (2010) Cell Metab 12, 283-94.
[3] Haack, T.B. et al. (2010) Nat Genet 42, 1131-4.

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