2'-AMINO-3'-HYDROXYACETOPHENONE Chemical Properties

Melting point:

182°C

Boiling point:

273.17°C (rough estimate)

Density 

1.2023 (rough estimate)

refractive index 

1.5810 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMF: 2 mg/ml; DMSO: 1 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 0.25 mg/ml

form 

powder to crystal

pka

8.94±0.10(Predicted)

color 

Light yellow to Amber to Dark green

InChI

InChI=1S/C8H9NO2/c1-5(10)6-3-2-4-7(11)8(6)9/h2-4,11H,9H2,1H3

InChIKey

DIIASMSSGMRMQF-UHFFFAOYSA-N

SMILES

C(=O)(C1=CC=CC(O)=C1N)C

CAS DataBase Reference

4502-10-7(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38-52

Safety Statements 

26-36/37/39

RTECS 

AM5950000

HS Code 

2922.50.4000

2'-AMINO-3'-HYDROXYACETOPHENONE Usage And Synthesis

Uses

1-(2-Amino-3-hydroxyphenyl)ethanone is the kynuridine metabolite, which could be extracted from rat liver mitochondrium. 1-(2-Amino-3-hydroxyphenyl)ethanone is associated with tryptophan metabolism disturbances, and can be used in bladder cancer, leukemia and anemia researches[1].

Preparation

Also obtained by bioconversion of nitro precursor using recombinant Escherichia coli strains.

References

[1] Kaseda H, et al., Biosynthetic routes to 2-aminoacetophenone and 2-amino-3-hydroxyacetophenone. J Biochem. 1973 Jul;74(1):127-33. DOI:10.1093/oxfordjournals.jbchem.a130215

2'-AMINO-3'-HYDROXYACETOPHENONE(4502-10-7)Related Product Information

• 2'-AMINO-3'-HYDROXYACETOPHENONE
• DISPERSE RED 60
• DISPERSE RED 4
• NUCLEAR FAST RED
• Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate
• Disperse Red 11
• Levofloxacin
• DISPERSE VIOLET 26
• Disperse Red 86
• Levofloxacin carboxylic acid
• 3-HYDROXY-DL-KYNURENINE
• 2-Acetyl-4-butyramidophenol
• 3amino-2hydroxyacetophenone (intermediate of pranlukast),3-Amino-2-hydroxyacetophenone
• 4'-Amino-2'-hydroxyacetophenone
• 3-AMINO-2-HYDROXYACETOPHENONE HYDROCHLORIDE,3'-AMINO-2'-HYDROXYACETOPHENONE HYDROCHLORIDE,3-AMINO-2-HYDROXYACETOPHENONE HCL
• 1-(3-hydroxyphenyl)-2-[methyl(phenylmethyl)amino]ethan-1-one
• 3'-Hydroxyacetophenone
• Acetophenone