3'-Hydroxyacetophenone Chemical Properties

Melting point:

90-95 °C(lit.)

Boiling point:

296 °C(lit.)

Density 

1.1 g/mL at 25 °C(lit.)

vapor pressure 

0.022Pa at 25℃

refractive index 

1,534

Flash point:

296°C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

22g/l

form 

Crystalline Powder

pka

9.19(at 25℃)

color 

Beige-brown

Water Solubility 

Soluble in alcohol. Insoluble in water.

BRN 

2040676

InChIKey

LUJMEECXHPYQOF-UHFFFAOYSA-N

LogP

1.144 at 25℃

CAS DataBase Reference

121-71-1(CAS DataBase Reference)

NIST Chemistry Reference

Ethanone, 1-(3-hydroxyphenyl)-(121-71-1)

EPA Substance Registry System

Ethanone, 1-(3-hydroxyphenyl)- (121-71-1)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

22-24/25-37/39-26-36

WGK Germany 

3

Hazard Note 

Harmful/Irritant

TSCA 

Yes

HS Code 

29143990

MSDS

• Language:English Provider:m-Hydroxyacetophenone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3'-Hydroxyacetophenone Usage And Synthesis

Description

3’-Hydroxyacetophenone is a chemical compound and it is a component of castoreum, the exudate from the castor sacs of the mature beaver. It is used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones.

Chemical Properties

beige-brown crystalline powder

Uses

Useful in the preparation of chalcones, flavonoids, and phenylephrine. It is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive.

Uses

3?Hydroxyacetophenone is used in the preparation of chalcones and flavonoids, which finds application as an anti-tuberculosis agent and antileishmanial chaocones. It is also involved in the preparation of phenylephrine. Further, it is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive.

Uses

3’Hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones.

Preparation

Preparation by diazotization of 3-aminoacetophenone, followed by hydrolysis of the obtained diazonium salt (78–82%).

General Description

3′-Hydroxyacetophenone is an hydroxy-substituted alkyl phenyl ketone.

Flammability and Explosibility

Non flammable

3'-Hydroxyacetophenone(121-71-1)Related Product Information

• 4'-Chloroacetophenone
• 3-Aminoacetophenone
• 4-Nitroacetophenone
• 3,5-Dihydroxyacetophenone
• 3-Nitroacetophenone
• 4'-Methoxyacetophenone
• Acetophenone
• 4'-Bromoacetophenone
• 6-Chloromethylmorphanthridine
• Eptifibatide non cyclic impurity
• 7-Bromo Epinastine
• Benzamide, N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-2-(hydroxymethyl)-
• L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→7)-disulfide (9CI)
• Methanone, (2-aminophenyl)phenyl-, hydrazone, (Z)-
• N-[2-(Phenylmethyl)phenyl]-2-chloroacetamide
• L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→1'),(6→6')-bis(disulfide)
• Cyclo(L-Pro-L-Trp-)
• Eptifibatide impurity 3/Deamidated Eptifibatide Impurity/(3R,11S,17S,20S,25aS)-20-((1H-indol-3-yl)Methyl)-17-(carboxymethyl)-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-3-carbo