CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID Chemical Properties

Boiling point:

442.2±24.0 °C(Predicted)

Density 

0.932±0.06 g/cm3(Predicted)

Flash point:

14℃

storage temp. 

-20°C

solubility 

0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible

form 

liquid

pka

4.76±0.10(Predicted)

EPA Substance Registry System

Docosapentaenoic (24880-45-3)

Safety Information

RIDADR 

UN1170 - class 3 - PG 2 - Ethanol

WGK Germany 

2

RTECS 

JR1320000

F 

8-10-23

MSDS

• Language:English Provider:SigmaAldrich

CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID Usage And Synthesis

Uses

A fatty acid use to inhibit platelet aggregation

Uses

all-cis-7,10,13,16,19-Docosapentaenoic Acid, also known as DPA, is a fatty acid derived from fish oils that potently inhibits platelet aggregation. DPA has been reported to block the cyclooxygenase pathway and stimulate the lipoxygenase pathway, which results in effective platelet aggregation inhibition. Peripheral blood mononuclear cell research demonstrates that DPA diminishes cyclooxygenase-2 levels intracellularly and inhibits pro-inflammatory prostaglandin E2 production.

Uses

CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.

Definition

ChEBI: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.

General Description

A Certified Spiking Solution^? suitable for use in mass spectrometry-based fatty acid testing applications such as assessment of cardiovascular disease risk and fatty acid deficiency, and detection and quantification of docosapentaenoic acid in nutraceuticals and dietary supplements. Docosapentaenoic acid (cis-7,10,13,16,19), also known as DPA, is an omega-3 fatty acid associated with neurological and ocular health benefits. Studies suggests that DPA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders.

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