HNMPA-(AM)3 Chemical Properties

Boiling point:

573.1±50.0 °C(Predicted)

Density 

1.325±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMF: 15 mg/ml; DMSO: 1 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 1 mg/ml

form 

Colorless oil.

color 

Colorless to light yellow

HNMPA-(AM)3 Usage And Synthesis

Definition

ChEBI: Hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester is an organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation. It has a role as a tyrosine kinase inhibitor. It is an organic phosphonate, a member of naphthalenes and an acetate ester. It is functionally related to a hydroxymethylphosphonic acid.

Biological Activity

Cell permeable: yes', 'Primary Target
tyrosine kinase', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 100 μM and 10 μM against insulin receptor tyrosine kinase and insulin-stimulated glucose oxidation in isolated r at adipocytes, respectively

HNMPA-(AM)3(120944-03-8)Related Product Information

• (-)PPP
• Hydroxy(2-naphthyl)Methanephosphonic Acid