Matrix Metalloproteinase-3 from Human, Recombinant
Matrix Metalloproteinase-3 from Human, Recombinant Basic information
- Product Name:
- Matrix Metalloproteinase-3 from Human, Recombinant
- Synonyms:
-
- Matrix Metalloproteinase-3 from Human, Recombinant
- CAS:
- 79955-99-0
- MW:
- 0
- Mol File:
- Mol File
Matrix Metalloproteinase-3 from Human, Recombinant Chemical Properties
- storage temp.
- -20°C
- form
- lyophilized
- biological source
- human
Matrix Metalloproteinase-3 from Human, Recombinant Usage And Synthesis
Uses
MCP-1 has been used to induce chemotaxis in mice macrophages.', 'MMP-3 human has been used to develop a simple and sensitive electrogenerated chemiluminescence (electrochemiluminescence (ECL)) peptide-based bioassay for the detection of matrix metalloproteinases releasing from living cells.
Biological Activity
Matrix metallopeptidase 3 (MMP3) has a broad substrate specificity and is capable of degrading fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. It participates in wound repair, progression of atherosclerosis, tissue remodeling and tumor initiation. MMP3 variants can be associated with hypertrophy of interventricular septum or hypertrophic cardiomyopathy.', 'The gene JE, also referred to as MCP-1 (monocyte chemoattractant protein-1), encodes a secreted chemokine th at functions as a chemoattractant for monocytes and may activate their anti-tumor properties. This protein may serve as a potential therapeutic anticancer agent.