H-ALA-PHE-OH Chemical Properties

Boiling point:

487.6±45.0 °C(Predicted)

Density 

1.222

storage temp. 

Sealed in dry,2-8°C

solubility 

Soluble in DMSO

pka

3.41±0.10(Predicted)

form 

Solid

color 

White to off-white

optical activity

36.6°(C=0.01978g/mL, H2O , 20°C, 589nm)

CAS DataBase Reference

3061-90-3(CAS DataBase Reference)

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

H-ALA-PHE-OH Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

Alanylphenylalanine is a potential antitumor agent that targets DNA via metal coordination. The complex of Alanylphenylalanine and Au (III) can bind to DNA and inhibit tumor cell proliferation[1][2].

Definition

ChEBI: A dipeptide formed from L-alanyl and L-phenylalanine residues.

Biological Activity

Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.

References

[1] Zhang ZH, et al. An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure. Sci Rep. 2016 Feb 23;6:22151. DOI:10.1038/srep22151
[2] Koleva B B, et al. The dipeptide alanylphenylalanine (H-Ala-Phe-OH)-protonation and coordination ability with Au (III)[J]. Journal of Molecular Structure, 2007, 831(1-3): 165-173.

H-ALA-PHE-OH(3061-90-3)Related Product Information

• H-ALA-PNA HCL
• H-Ala-Glu-OH.HCl
• L-ALANYL-L-TYROSINE
• L-Alanine benzyl ester hydrochloride
• H-Ala-AMC.HCL
• L-ALANYL-L-TRYPTOPHAN
• L-Alanyl-L-proline
• L-Alanine methyl ester hydrochloride
• L-Alaninamide hydrochloride
• L-Alanine isopropyl ester hydrochloride
• L-Alanyl-L-Glutamine
• L-Alanine benzyl ester 4-toluenesulfonate
• TYRAMINE HYDROCHLORIDE
• Aspartame
• N-CBZ-VAL-TYR METHYL ESTER
• Z-VAL-PHE-OH
• H-MET-TYR-OH
• Z-TYR-TYR-OH