PHTHALAMIC ACID Chemical Properties

Melting point:

140-143 °C(lit.)

Boiling point:

394.2±25.0 °C(Predicted)

Density 

1.368

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

3.75±0.10(Predicted)

color 

White to Off-White

BRN 

1868205

CAS DataBase Reference

88-97-1(CAS DataBase Reference)

EPA Substance Registry System

Benzoic acid, 2-(aminocarbonyl)- (88-97-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

2924297099

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

PHTHALAMIC ACID Usage And Synthesis

Uses

Phthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity.

Uses

Phthalamic acid may be used to synthesize anthranilic acid via reaction with sodium hypochlorite.

Definition

ChEBI: 2-carbamoylbenzoic acid is a carbamoylbenzoic acid.

General Description

Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (k_obs) as 5.1×10^-5sec^-1 at pH 1.3-1.8 and 35^°C. It undergoes hydrolysis about 105 times faster than benzamide.

PHTHALAMIC ACID(88-97-1)Related Product Information

• N-(4-THIOPHEN-2-YL-THIAZOL-2-YL)-PHTHALAMIC ACID
• N-(1-NAPHTHYL)PHTHALAMIC ACID,N-NAPHTHALEN-1-YL-PHTHALAMIC ACID
• PHTHALANILLIC ACID
• N-(4-(acetylsulphamoyl)phenyl)phthalamic acid
• Phthalylsulfathiazole
• PHTHALAMIC ACID
• (S)-(-)-N-(1-PHENYLETHYL)PHTHALAMIC ACID
• (R)-(+)-N-(1-PHENYLETHYL)PHTHALAMIC ACID
• N,N-DIETHYL-PHTHALAMIC ACID ETHYL ESTER
• N-(4-METHOXY-PHENYL)-PHTHALAMIC ACID
• N-Metatolyl phthalamic acid
• 2-[[(2-CHLOROPHENYL)AMINO]CARBONYL]-BENZOIC ACID
• 2-{[(3-CHLOROPHENYL)AMINO]CARBONYL}-BENZOIC ACID
• N-(2,5-DIMETHYL-PHENYL)-PHTHALAMIC ACID
• Ftaxilide
• 4'-SULFAMOYLPHTHALANILIC ACID
• N,N-BIS[(S)-(-)-1-PHENYLETHYL]PHTHALAMIC ACID,N,N-BIS((S)-1-PHENYLETHYL) PHTHALAMIC ACID
• o-Phthalamic acid