ACA
ACA Basic information
- Product Name:
- ACA
- Synonyms:
-
- AMARANTHUS CAUDATUS LECTIN
- ACA
- ACL
- 2-[[1-oxo-3-(4-Pentylphenyl)-2-propen-1-yl]amino]-benzoic acid
- N-(4-Pentylcinnamoyl)anthranilic acid
- GAMRBCZMOOMBSQ-CCEZHUSRSA-N
- 2-[3-(4-pentylphenyl)prop-2-enoylamino]benzoic acid
- N-(p-Amylcinnamoyl)anthranilic acid >=98% (HPLC)
- CAS:
- 99196-74-4
- MF:
- C21H23NO3
- MW:
- 337.41
- Mol File:
- 99196-74-4.mol
ACA Chemical Properties
- Boiling point:
- 563.1±50.0 °C(Predicted)
- Density
- 1.178±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: ≥20mg/mL
- pka
- 3.46±0.36(Predicted)
- form
- powder
- color
- white to off-white
ACA Usage And Synthesis
Uses
N-(p-Amylcinnamoyl)anthranilic acid has been used as a transient receptor potential cation channel subfamily M member 2 (TRPM2) inhibitor, in studying its role in regulating the production of reactive oxygen species (ROS).
Definition
ChEBI: N-(p-amylcinnamoyl)anthranilic acid is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor. It has a role as an EC 3.1.1.4 (phospholipase A2) inhibitor and a TRP channel blocker. It is an amidobenzoic acid, a member of cinnamamides and a secondary carboxamide.
General Description
N-(p-Amylcinnamoyl)anthranilic acid (ACA) functions as a broad spectrum phospholipase A2 inhibitor and blocks transient receptor potential (TRP) channels. It inhibits calcium activated chloride current in cardiac ventricular myocytes. ACA regulates various ion channels.
Biochem/physiol Actions
Broad spectrum phospholipase A2 (PLA2) inhibitor and TRP channel blocker.