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(25R)-Spirost-4-en-3,12-dion

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(25R)-Spirost-4-en-3,12-dion Basic information

Product Name:
(25R)-Spirost-4-en-3,12-dion
Synonyms:
  • (25R)-Spirost-4-en-3,12-dion
  • Spirost-4-ene-3,12-dione, (25R)-
  • 25R-spirost-4-ene-3,12-dione
  • 25D-Spirost-4-ene-3,12-dione
  • (-)-(25R)-Spirost-4-ene-3,12-dione
  • natural product,neutrophil,mast cells,histamine,Inhibitor,(25R)Spirost4ene3,12dione,inhibit,(25R) Spirost 4 ene 3,12 dione
  • (25R)-Spirost-4-ene-3,12-dione-(25R)-Spirost-4-ene-3,12-dione
  • (25R)-Spirost-4-ene-3,12-dione - [S88757]
CAS:
6875-60-1
MF:
C27H38O4
MW:
426.59
Mol File:
6875-60-1.mol
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(25R)-Spirost-4-en-3,12-dion Chemical Properties

form 
Solid
color 
White to off-white
InChIKey
ZVWYBBDTSJOAHD-HGMFYQPQSA-N
SMILES
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](C(=O)C1)(C)[C@]1([C@H](C)[C@@]4(CC[C@@H](C)CO4)O[C@@]1([H])C3)[H])CC2
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(25R)-Spirost-4-en-3,12-dion Usage And Synthesis

Uses

(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells[1].

References

[1] P L Tsai, et al. Constituents and bioactive principles of Polygonum chinensis. Phytochemistry. 1998 Nov;49(6):1663-6. DOI:10.1016/s0031-9422(98)00322-7

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