N6,N6-Dimethyl-4’-thio-adenosine Chemical Properties

Boiling point:

599.6±60.0 °C(Predicted)

Density 

1.72±0.1 g/cm3(Predicted)

pka

13.04±0.70(Predicted)

N6,N6-Dimethyl-4’-thio-adenosine Usage And Synthesis

Uses

N6,N6-Dimethyl-4’-thio-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

N6,N6-Dimethyl-4’-thio-adenosine(25795-69-1)Related Product Information

• N6,N6-Dimethyl-2'-O-methyladenosine
• N6,N6-Dimethyl-2'-C-methyladenosine
• N6,N6-Dimethyl-xylo-adenosine
• N6,N6-Dimethyl-3'-beta-C-methyl- adenosine