N6,N6-Dimethyl-xylo-adenosine
N6,N6-Dimethyl-xylo-adenosine Basic information
- Product Name:
- N6,N6-Dimethyl-xylo-adenosine
- Synonyms:
-
- N6,N6-Dimethyl-xylo-adenosine
- 9H-Purin-6-amine, N,N-dimethyl-9-β-D-xylofuranosyl-
- (2R,3R,4R,5R)-2-(6-(dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- CAS:
- 669055-52-1
- MF:
- C12H17N5O4
- MW:
- 295.3
- Mol File:
- 669055-52-1.mol
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N6,N6-Dimethyl-xylo-adenosine Chemical Properties
- Boiling point:
- 607.3±65.0 °C(Predicted)
- Density
- 1.71±0.1 g/cm3(Predicted)
- pka
- 13.11±0.70(Predicted)
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N6,N6-Dimethyl-xylo-adenosine Usage And Synthesis
Uses
N6,N6-Dimethyl-xylo-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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