NF110
NF110 Basic information
- Product Name:
- NF110
- Synonyms:
-
- NF110
- 4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonicacidtetrasodiumsalt
- 4-[[3-[[3,5-bis[(4-sulfonatophenyl)carbamoyl]phenyl]carbamoylamino]-5-[(4-sulfonatophenyl)carbamoyl]benzoyl]amino]benzenesulfonate
- CAS:
- 111150-22-2
- MF:
- C41H28N6O17S4.4Na
- MW:
- 1096.92
- Mol File:
- 111150-22-2.mol
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NF110 Chemical Properties
- storage temp.
- Desiccate at RT
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 40 mM in water
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NF110 Usage And Synthesis
Uses
NF 110 is a potent P2X3 receptor antagonist.
Biological Activity
High affinity P2X 3 receptor antagonist (K i values are 36, 82 and 4144 nM for P2X 3 , P2X 1 and P2X 2 recombinant receptors respectively). Shows no activity at P2Y 1 , P2Y 2 and P2Y 11 receptors (IC 50 > 10 μ M). Potently inhibits α , β -meATP-evoked desensitizing currents in rat DRG neurons (IC 50 = 527 nM). Shows antitumor activity against several tumor types.
storage
Desiccate at RT
NF110Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
BOC Sciences
- Tel
- info@bocsci.com
Career Henan Chemica Co
- Tel
- +86-0371-86658258 +8613203830695
- laboratory@coreychem.com
Hubei Xinyang Medical Technology Co., Ltd
- Tel
- 15347293736 15347293736
- 2853117764@qq.com