Basic information Safety Supplier Related

3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

Basic information Safety Supplier Related

3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Basic information

Product Name:
3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
Synonyms:
  • 3-(2-chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide
  • IfofaMide acylation objects
  • (R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone
  • IFOSFAMIDEACYLATE
  • 3-(2-CHLOROACETYL)-2-[(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE-2-OXIDE
  • 3-(2-CHLOROACTYL)-2-[(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE-2-OXIDE ,98%
  • Ifosfamide acylation objects
  • IfosfamideIntermediate
CAS:
72578-71-3
MF:
C7H13Cl2N2O3P
MW:
275.07
EINECS:
1806241-263-5
Mol File:
72578-71-3.mol
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3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Chemical Properties

Boiling point:
355.0±52.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-1.29±0.20(Predicted)
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3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

(R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone is an intermediate in the preparation of Ifosfamide (I265000), a cytostatic agent, related structurally to cyclophosphamide.

Uses

antineoplastic agent and antimetabolite

3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideSupplier

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