N-ACETYL-L-TYROSINE ETHYL ESTER Chemical Properties

Melting point:

78-81 °C

Boiling point:

394.43°C (rough estimate)

Density 

1.1667 (rough estimate)

refractive index 

22 ° (C=1, EtOH)

storage temp. 

Sealed in dry,2-8°C

pka

9.75±0.15(Predicted)

Water Solubility 

3.48g/L(28 ºC)

LogP

0.592 (est)

CAS DataBase Reference

840-97-1(CAS DataBase Reference)

EPA Substance Registry System

L-Tyrosine, N-acetyl-, ethyl ester (840-97-1)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich

N-ACETYL-L-TYROSINE ETHYL ESTER Usage And Synthesis

Definition

ChEBI: Ethyl N-acetyl-L-tyrosinate is an L-tyrosine derivative that is the ethyl ester of N-acetyltyrosine. It is an ethyl ester, a member of acetamides, a member of phenols and a L-tyrosine derivative.

Enzyme inhibitor

This ester (FW = 251.28 g/mol; Abbreviation ATEE) is a substrate for chymotrypsin that is frequently used in assays of that enzyme. The reaction can be followed by observing the production of free carboxyl groups or by the decrease in absorbance at 237 nm and pH 7. Supersaturated stock solutions (i.e., 10-20 mM) can be prepared by dissolving ATEE in water at 85°C, followed by rapidly cooling to room temperature. These solutions are typically stable for six to twelve hours. N-Acetyl-L-tyrosine ethyl ester inhibits protein-disulfide reductase, glutathione-requiring; thiolsubtilisin; complement component C’.

N-ACETYL-L-TYROSINE ETHYL ESTER(840-97-1)Related Product Information

• N-Acetyl-L-methionine
• N-Acetyl-L-isoleucine
• AC-LYS-OH
• N-乙酰-L-谷氨酸
• N-Acetyl-L-cysteine
• N-Acetyl-L-tryptophan
• N-Acetyl-DL-methionine
• N-Acetyl-L-phenylalanine
• N-Acetyl-L-glutamine
• N-Acetyl-L-proline
• N-Acetyl-L-tyrosine
• Ethyl L-tyrosinate
• L-Tyrosine
• Methyl L-tyrosinate
• Ethyl N-acetyl-L-tyrosinate hydrate
• N-Acetyl-L-tyrosine Ethyl Ester, Monohydrate (1.00083)
• N-ACETYL-L-TYROSINE ETHYL ESTER MONOHYDRATE (ATEE)