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N-Acetyl-L-tryptophan

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N-Acetyl-L-tryptophan Basic information

Product Name:
N-Acetyl-L-tryptophan
Synonyms:
  • ACETYL-L-TRYPTOPHANE
  • ACETYL-L-TRYPTOPHAN
  • AC-TRP-OH
  • AC-TRYPTOPHAN
  • L-N-ACETYL-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
  • (S)-2-acetaMido-3-(1H-indol-3-yl)propanoic acid
  • Tryptophan Related CoMpound B
  • N-Ac-Tryptohan
CAS:
1218-34-4
MF:
C13H14N2O3
MW:
246.26
EINECS:
214-935-9
Product Categories:
  • Amino Acids Derivatives
  • Amino Acid Derivatives
  • A - H
  • Amino Acids
  • amino acid
  • amino
  • Tryptophan [Trp, W]
  • Amino Acids and Derivatives
  • Ac-Amino Acids
  • Amino Acids (N-Protected)
  • Biochemistry
  • Indoles
  • Tryptophans
  • Modified Amino Acids
  • Amino Acids
  • N-Acetyl-Amino acid series
Mol File:
1218-34-4.mol
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N-Acetyl-L-tryptophan Chemical Properties

Melting point:
186°C
alpha 
+24.0~+30.0°(20℃/D)(c=1,C2H5OH)
Boiling point:
389.26°C (rough estimate)
Density 
1.1855 (rough estimate)
refractive index 
1.6450 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.65±0.10(Predicted)
form 
Powder
color 
White to Off-white
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
0.702 (est)
CAS DataBase Reference
1218-34-4(CAS DataBase Reference)
NIST Chemistry Reference
L-tryptophan, n-acetyl-(1218-34-4)
EPA Substance Registry System
L-Tryptophan, N-acetyl- (1218-34-4)
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Safety Information

WGK Germany 
2
RTECS 
YN6160000
TSCA 
Yes
HS Code 
29339900

MSDS

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N-Acetyl-L-tryptophan Usage And Synthesis

Chemical Properties

solid

Uses

N-Acetyl-L-Tryptophan, is a derivative of L-Tryptophan (T947210), that can be used as competitive inhibitor to identify and characterize tryptophanases. It can also be used as an NK1 tachykinin receptor antagonist, that may help to develop a novel therapeutic intervention for the treatment of reperfusion injury in acute ischemic stroke.

Definition

ChEBI: A N-acetyl-L-amino acid that is the N-acetyl derivative of L-tryptophan.

Safety Profile

Moderately toxic by some routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOX,.

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