N-Acetyl-L-tryptophan
N-Acetyl-L-tryptophan Basic information
- Product Name:
- N-Acetyl-L-tryptophan
- Synonyms:
-
- ACETYL-L-TRYPTOPHANE
- ACETYL-L-TRYPTOPHAN
- AC-TRP-OH
- AC-TRYPTOPHAN
- L-N-ACETYL-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
- (S)-2-acetaMido-3-(1H-indol-3-yl)propanoic acid
- Tryptophan Related CoMpound B
- N-Ac-Tryptohan
- CAS:
- 1218-34-4
- MF:
- C13H14N2O3
- MW:
- 246.26
- EINECS:
- 214-935-9
- Product Categories:
-
- Amino Acids Derivatives
- Amino Acid Derivatives
- A - H
- Amino Acids
- amino acid
- amino
- Tryptophan [Trp, W]
- Amino Acids and Derivatives
- Ac-Amino Acids
- Amino Acids (N-Protected)
- Biochemistry
- Indoles
- Tryptophans
- Modified Amino Acids
- Amino Acids
- N-Acetyl-Amino acid series
- Mol File:
- 1218-34-4.mol
N-Acetyl-L-tryptophan Chemical Properties
- Melting point:
- 186°C
- alpha
- +24.0～+30.0°(20℃/D)(c=1,C2H5OH)
- Boiling point:
- 389.26°C (rough estimate)
- Density
- 1.1855 (rough estimate)
- refractive index
- 1.6450 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 3.65±0.10(Predicted)
- form
- Powder
- color
- White to Off-white
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- 0.702 (est)
- CAS DataBase Reference
- 1218-34-4(CAS DataBase Reference)
- NIST Chemistry Reference
- L-tryptophan, n-acetyl-(1218-34-4)
- EPA Substance Registry System
- L-Tryptophan, N-acetyl- (1218-34-4)
MSDS
- Language:English Provider:SigmaAldrich
N-Acetyl-L-tryptophan Usage And Synthesis
Chemical Properties
solid
Uses
N-Acetyl-L-Tryptophan, is a derivative of L-Tryptophan (T947210), that can be used as competitive inhibitor to identify and characterize tryptophanases. It can also be used as an NK1 tachykinin receptor antagonist, that may help to develop a novel therapeutic intervention for the treatment of reperfusion injury in acute ischemic stroke.
Definition
ChEBI: A N-acetyl-L-amino acid that is the N-acetyl derivative of L-tryptophan.
Biological Activity
N-Acetyl-L-tryptophan (NAT, Ac-Trp-OH) is used a substance P NK1 tachykinin receptor antagonist. N-Acetyl-L-tryptophan is also used as a competitive inhibitor to identify, differentiate and characterized tryptophanase(s).
Safety Profile
Moderately toxic by some routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOX,.
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N-Acetyl-L-tryptophan(1218-34-4)Related Product Information
- L-5-Hydroxytryptophan
- Acetylacetone
- L-Tryptophan
- Acetyl chloride
- Acetyl coenzyme A sodium salt
- N-Acetyl-L-cysteine
- N-Acetyl-L-isoleucine
- 2-Acetylaminopropionic acid
- N-Acetyl-L-asparagine
- N-Acetyl-L-valine
- N-ACETYL-D-PHENYLALANINE
- 2-Acetylamino-propionic acid
- N-Acetyl-D-methionine
- N-Acetyl-DL-aspartic acid
- AC-ALA-NH2
- N-Acetylneuraminic acid
- 5-Hydroxytryptophan
- 2-(1H-indol-3-yl)acetaldehyde