Basic information Safety Supplier Related

clofexamide

Basic information Safety Supplier Related

clofexamide Basic information

Product Name:
clofexamide
Synonyms:
  • clofexamide
  • 2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
  • Amichlophene
  • Chlofexamide
  • IEM-455
  • NP-246
  • ANP 246
  • ANP246
CAS:
1223-36-5
MF:
C14H21ClN2O2
MW:
284.78
EINECS:
2149516
Mol File:
1223-36-5.mol
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clofexamide Chemical Properties

Melting point:
45 °C
Boiling point:
124.5°C (rough estimate)
Density 
1.1742 (rough estimate)
refractive index 
1.5200 (estimate)
pka
14.19±0.46(Predicted)
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Safety Information

Toxicity
LD50 oral in rat: 1040mg/kg
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clofexamide Usage And Synthesis

Originator

Clofexamide ,CNRS

Manufacturing Process

In 1 L of water there is dissolved 116.0 g (1 mole) of N,Ndiethylethylenediamine and, under vigorous stirring at a temperature maintained below 50°C, there is added 205.0 g (1 mole) of the chloride of pchlorphenoxyacetic acid. The solution becomes rapidly homogeneous; the formation of the basic amide hydrochloride is rapidly completed by further stirring the reaction mixture for 2 h at about 20°C. Then an excess of soda lye is added and the basic amide formed is extracted by ether. The ethereal solution is dried on anhydrous sodium sulfate and ether is distilled after that the residue is dried. So 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl) acetamide is obtained.

Therapeutic Function

Antidepressant, Analgesic, Antiinflammatory, Local anesthetic

clofexamide Supplier

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Career Henan Chemica Co
Tel
+86-0371-86658258 15093356674;
Email
laboratory@coreychem.com
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Shaoguan Qicheng Biotechnology Co., Ltd
Tel
18122215013
Email
780229652@qq.com