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Prednisolone 21-trimethylacetate

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Prednisolone 21-trimethylacetate Basic information

Product Name:
Prednisolone 21-trimethylacetate
Synonyms:
  • 11β,17-Dihydroxy-21-(2,2-dimethyl-1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • 21-(Pivaloyloxy)-11β,17-dihydroxypregna-1,4-diene-3,20-dione
  • [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] 2,2-dimethylpropanoate
  • [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] 2,2-dimethylpropanoate
  • 2,2-dimethylpropionic acid [2-(11,17-dihydroxy-3-keto-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-keto-ethyl] ester
  • 21-Trimethylacetate
  • Prednisolone pivalate Solution, 100ppm
  • prednisolone 21-pivalate
CAS:
1107-99-9
MF:
C26H36O6
MW:
444.56044
EINECS:
214-172-1
Mol File:
1107-99-9.mol
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Prednisolone 21-trimethylacetate Chemical Properties

Melting point:
233-236°
alpha 
D26 +103° (c = 1.208 in chloroform); D20 +97.5° (c = 1 in chloroform)
Boiling point:
597.3±50.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
solubility 
Practically insoluble in water, slightly soluble in ethanol (96 per cent), soluble in methylene chloride.
pka
12.34±0.70(Predicted)
Stability:
Moisture Sensitive
CAS DataBase Reference
1107-99-9
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Prednisolone 21-trimethylacetate Usage And Synthesis

Chemical Properties

White or almost white, crystalline powder.

Uses

Prednisolone Pivalate is a metabolite of Prednisolone (P703740), which is a synthetic corticosteroid; metabolically interconvertible with prednisone.

Uses

Glucocorticoid.

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