β-Tubulin Antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey;Zebrafish;Bovine

Background

The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments, and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins.

References

[1] Westermann, S. and Weber, K. (2003) Nat Rev Mol Cell Biol 4, 938-47.

β-Tubulin Antibody()Related Product Information

• β-Tubulin (D2N5G) Rabbit mAb
• β-Tubulin (D3U1W) Mouse mAb
• β-Tubulin (9F3) Rabbit mAb (HRP Conjugate)