Basic information Safety Supplier Related

(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID

Basic information Safety Supplier Related

(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID Basic information

Product Name:
(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID
Synonyms:
  • (5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID
  • 5(S), 12(S)-DIHETE
  • 5(S),12(S)-DIHYDROXYEICOSA-6E,8E,10E,14Z-TETRAENOIC ACID
  • 6-TRANS-12-EPI LEUKOTRIENE B4
  • 6-TRANS-12-EPI-LTB4
  • 6E-12-EPI-LEUKOTRIENE B4
  • (5S,6E,8E,10E,12S,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
  • 6-trans-12-epi Leukotriene B4 Lipid Maps MS Standard
CAS:
71548-19-1
MF:
C20H32O4
MW:
336.47
Mol File:
71548-19-1.mol
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(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID Chemical Properties

Boiling point:
536.4±50.0 °C(Predicted)
Density 
1.040±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka
4.66±0.10(Predicted)
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Safety Information

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1170 3/PG 2
WGK Germany 
3

MSDS

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(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID Usage And Synthesis

Uses

6-trans-12-epi Leukotirene B4 (LTB4) is a non-enzymatic hydrolysis product of LTA4. It was originally isolated from glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNL). 6-trans-12-epi LTB4 is weakly chemotactic for PMNL, with approximately 20 times less potency than LTB4, and has no effect on the aggregation response.

Uses

6-trans-12-epi Leukotriene B4 is a product of the non-enzymatic hydrolysis of LTA4.

Definition

ChEBI: A leukotriene that is the 6-trans,12S-isomer of leukotriene B4.

(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACIDSupplier

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