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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Biochemical Reagents >  Agonist Inhibitors >  Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)-

Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)-

Basic information Safety Supplier Related

Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)- Basic information

Product Name:
Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)-
Synonyms:
  • Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)-
  • MK2118
  • STING agonist MK-2118
CAS:
2218504-06-2
MF:
C15H16O5S
MW:
308.35
Mol File:
2218504-06-2.mol
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Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)- Chemical Properties

Boiling point:
509.0±50.0 °C(Predicted)
Density 
1.300±0.06 g/cm3(Predicted)
pka
4.39±0.23(Predicted)
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Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)- Usage And Synthesis

Uses

MK-2118 is a GMP-synthesized STING agonist with the potential to inhibit advanced/metastatic solid tumors or lymphomas.[1].

References

[1] Lyons T W, Thaisrivongs D A, Kuhl N, et al. The First GMP Synthesis of MK-2118, a Small Molecule Agonist for Stimulator of Interferon Genes[J]. Organic Process Research & Development, 2024.

Benzo[b]thiophene-2-butanoic acid, 5,6-dimethoxy-α-methyl-γ-oxo-, (αS)-Supplier

ShangHai Caerulum Pharma Discovery Co., Ltd.
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