Sulfamonomethoxine-d3
Sulfamonomethoxine-d3 Basic information
- Product Name:
- Sulfamonomethoxine-d3
- Synonyms:
-
- 4-amino-N-[6-(trideuteriomethoxy)pyrimidin-4-yl]benzenesulfonamide
- Sulfamonomethoxine-d3-1
- CAS:
- 2704162-84-3
- MF:
- C11H9D3N4O3S
- MW:
- 283.32
- Mol File:
- 2704162-84-3.mol
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Sulfamonomethoxine-d3 Chemical Properties
- Boiling point:
- 513.247±60.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.465±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
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Sulfamonomethoxine-d3 Usage And Synthesis
Uses
Sulfamonomethoxine-d3-1 is the deuterium labeled Sulfamonomethoxine[1]. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate[2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Ryuji Ueno. Pharmacokinetics and Bioavailability of Sulfamonomethoxine in Cultured Eel. Fish Pathology,33(4),297-301,1998.10.