INDEX NAME NOT YET ASSIGNED Chemical Properties

solubility 

DMSO: slightly soluble; Methanol: slightly soluble

form 

A solid

INDEX NAME NOT YET ASSIGNED Usage And Synthesis

Description

Sulfamethizole-d₄ is intended for use as an internal standard for the quantification of sulfamethizole by GC- or LC-MS. Sulfamethizole is a broad-spectrum sulfonamide antibiotic (MIC₉₀s = 1.25-5,000 μg/ml against clinical isolates of E. coli and K. pneumoniae).¹ It inhibits dihydropteroate synthase, an enzyme involved in folate biosynthesis. Formulations containing sulfamethizole have previously been used to treat urinary tract infections.

References

1. Wambaugh, M.A., Shakya, V.P.S., Lewis, A.J., et al. High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance PLoS Biol. 15(6):e2001644,(2017).

INDEX NAME NOT YET ASSIGNED(2470130-12-0)Related Product Information

• SULFATHIAZOLE-D4
• Sulfadimethoxine-d6
• Sulfamethazine-D4
• 4-amino-2,3,5,6-tetradeuterio-N-quinoxalin-2-ylbenzenesulfonamide
• SULFAMERAZIN-D4
• 4-amino-2,3,5,6-tetradeuterio-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
• SulphanilaMide-d4
• INDEX NAME NOT YET ASSIGNED