Fmoc-N-methyl-L-isoleucine Chemical Properties

Melting point:

177-183 °C

Boiling point:

537.3±29.0 °C(Predicted)

Density 

1.194±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in water or 1% acetic acid

pka

3.94±0.22(Predicted)

form 

Solid

color 

White to Almost white

optical activity

[α]20/D 59±2°, c = 1% in DMF

BRN 

7548444

InChI

InChI=1S/C22H25NO4/c1-4-14(2)20(21(24)25)23(3)22(26)27-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,4,13H2,1-3H3,(H,24,25)/t14-,20-/m0/s1

InChIKey

IQIOLCJHRZWOLS-XOBRGWDASA-N

SMILES

C(O)(=O)[C@H]([C@@H](C)CC)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C

CAS DataBase Reference

138775-22-1(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2924 29 70

MSDS

• Language:English Provider:SigmaAldrich

Fmoc-N-methyl-L-isoleucine Usage And Synthesis

Chemical Properties

White powder

Uses

Fmoc-N-Me-Ile-OH is a useful intermediate used in the total synthesis of Nannocystin A, a 21-membered cyclodepsipeptide with anticancer properties.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Fmoc-N-methyl-L-isoleucine(138775-22-1)Related Product Information

• FMOC-N-Methyl-L-alanine
• FMOC-SARCOSINE MONOHYDRATE
• Fmoc-N-Me-Arg(pbf)-OH
• Fmoc-N-methyl-L-glutamic acid 5-tert-butyl ester
• FMOC-D-HIS(FMOC)-OH
• Fmoc-N-Me-D-Ser(tBu)-OH
• Fmoc-N-methyl-D-leucine
• Fmoc-D-Me-Ala-OH
• Fmoc-N-methyl-O-benzyl-L-threonine
• FMoc-N-Me-His(Trt)-OH
• (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid
• Fmoc-N-Me-Lys(Boc)-OH
• FMOC-N-ME-ARG(MTR)-OH
• Fmoc-N-methyl-L-phenylalanine
• FMoc-N-Me-Asn(trt)-OH
• (9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-Orn(Boc)-OH
• N-Fmoc-N-Methyl-O-tert-butyl-L-serine
• Fmoc-N-methyl-D-phenylalanine