BIS(TRIMETHYLSILYL) MALONATE Chemical Properties

Melting point:

56 °C

Boiling point:

63-66 °C/1 mmHg (lit.)

Density 

0.974 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.416(lit.)

Flash point:

75 °F

storage temp. 

2-8°C

form 

Liquid

pka

12.18±0.46(Predicted)

color 

Clear colorless to straw

Specific Gravity

0.97

Hydrolytic Sensitivity

7: reacts slowly with moisture/water

BRN 

2212115

InChIKey

ATCKJLDGNXGLAO-UHFFFAOYSA-N

CAS DataBase Reference

18457-04-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

16

RIDADR 

UN 3272 3/PG 2

WGK Germany 

3

F 

10-21

TSCA 

No

HazardClass 

3.2

PackingGroup 

III

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich

BIS(TRIMETHYLSILYL) MALONATE Usage And Synthesis

Chemical Properties

clear colorless to straw colored liquid

Uses

Bis(trimethylsilyl) malonate was used as cyclocondensation agent in cyclocondensation reactions. It was also used in the preparation of β-keto acids and methyl ketones.

General Description

Bis(trimethylsilyl) malonate is precursor for metal-organic chemical vapor deposition (MOCVD) of HfO₂ and ZrO₂ thin films. It undergoes acylation reaction with acid chlorides and acyl carbonates in the presence of triethylamine and magnesium or lithium salts to give β-keto acids or methyl ketones.

Synthesis

Bis(trimethylsilyl) Malonate can be easily prepared from malonic acid by a number of silylation procedures. It is a reagent useful in the synthesis of β-keto acids and methyl ketones.

References

[1] Tetrahedron, 2016, vol. 72, # 37, p. 5713 - 5723
[2] Canadian Journal of Chemistry, 1972, vol. 50, p. 3913 - 3916

BIS(TRIMETHYLSILYL) MALONATE(18457-04-0)Related Product Information

• Avatrombopag maleate
• Maleic acid ricinoleate
• Malonic acid
• BIS(TRIMETHYLSILYL) MALONATE
• METHOXYTRIMETHYLSILANE
• Ethoxytrimethylsilane
• Trimethyl(propoxy)silane
• DIMETHYLETHOXYSILANE
• Trimethylsilyl acetate
• TRIMETHYLSILYL PROPIONATE
• DIMETHYLACETOXYSILANE
• DIMETHYLMETHOXYSILANE