glycine linoleamide Chemical Properties

Melting point:

0.150 °C (approx)

Boiling point:

530.7±43.0 °C(Predicted)

Density 

0.974±0.06 g/cm3(Predicted)

RTECS 

MC0596320

solubility 

DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 2 mg/ml

form 

Solid

pka

3.59±0.10(Predicted)

glycine linoleamide Usage And Synthesis

Uses

Linoleoyl glycine is a modified polyunsaturated fatty acid. Linoleoyl glycine has activating effects on human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in Xenopus oocytes[1].

Definition

ChEBI: N-linoleoylglycine is a N-acyl-amino acid. It is a conjugate acid of a N-linoleoylglycine(1-).

References

[1] Skarsfeldt MA, et al. Polyunsaturated fatty acid-derived IKs channel activators shorten the QT interval ex-vivo and in-vivo. Acta Physiol (Oxf). 2020;229(4):e13471. DOI:10.1111/apha.13471