Basic information Safety Supplier Related

dutomycin

Basic information Safety Supplier Related

dutomycin Basic information

Product Name:
dutomycin
Synonyms:
  • dutomycin
  • 1,4,6,7(6aH,10H)-Naphthacenetetrone, 8-acetyl-10-[[5-[[2,6-dideoxy-4-O-(2,4-dimethyl-1-oxo-2-heptenyl)-3-C-methyl-α-L-xylo-hexopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-10a,11-dihydro-5,6a,9,10a-tetrahydroxy-2-methoxy-12-methyl-, [2S-[2α(6aR*,10S*,10aS*),5β(2Z,4S*),6α]]- (9CI)
CAS:
146663-67-4
MF:
C44H54O17
MW:
854.89
Mol File:
146663-67-4.mol
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dutomycin Chemical Properties

Boiling point:
1023.6±65.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
pka
4.05±0.70(Predicted)
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dutomycin Usage And Synthesis

Definition

ChEBI: Dutomycin is an anthracycline antibiotic of formula C44H54O17 isolated from Streptomyces species. It directly binds to the human serine protease inhibitor B6 (SERPINB6), inducing autophagy and apoptosis. It has a role as a bacterial metabolite, an autophagy inducer, an apoptosis inducer and an antineoplastic agent. It is an anthracycline antibiotic, a tertiary alpha-hydroxy ketone, a member of phenols, an ether, a member of 1,4-benzoquinones, a disaccharide derivative, an enol, an enoate ester, a carbopolycyclic compound and a carbohydrate-containing antibiotic.

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