CYCLOPROPANECARBOTHIOAMIDE Chemical Properties

Melting point:

111-113℃

Boiling point:

176.9±23.0 °C(Predicted)

Density 

1.272±0.06 g/cm3(Predicted)

pka

13.19±0.20(Predicted)

CAS DataBase Reference

20295-34-5

Safety Information

HazardClass 

IRRITANT

HS Code 

2930909899

CYCLOPROPANECARBOTHIOAMIDE Usage And Synthesis

Description

Cyclopropanecarbothioamide is used for purification of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas during the simple-step reaction. It is also a useful chemical during the proteomics study. Recent study has also used it for synthesis of a novel heterocyclic compound, CE-125, which can improve working memory in the radial arm maze and modulate the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.

Uses

Cyclopropanecarbothioamide is used for purification in single-step preparation of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas.

References

https://www.alfa.com/en/catalog/H32315/
Hussein, A. M., et al. "A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat." Behavioural Brain Research 332(2017):308-315.

CYCLOPROPANECARBOTHIOAMIDE(20295-34-5)Related Product Information

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