CYCLOPROPANECARBOXYLIC ACID HYDRAZIDE Chemical Properties

Melting point:

98-99℃

Boiling point:

283.0±7.0 °C(Predicted)

Density 

1.244±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

13.46±0.20(Predicted)

Appearance

White to off-white Solid

CAS DataBase Reference

6952-93-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

RIDADR 

UN2811

HazardClass 

IRRITANT

HS Code 

2928009090

CYCLOPROPANECARBOXYLIC ACID HYDRAZIDE Usage And Synthesis

Synthesis

General procedure for the synthesis of cyclopropanecarboxylic acid hydrazide from methyl cyclopropanecarboxylate: Methyl cyclopropanecarboxylate (10 g, 0.1 mol) was mixed with hydrazine hydrate (7.3 mL, 0.15 mol), and the reaction was carried out at reflux for 28 h and then cooled to room temperature. The reaction mixture was concentrated by evaporation under reduced pressure, followed by azeotropic distillation through toluene to remove residual water. The crude product obtained was dissolved in dichloromethane and washed with saturated sodium chloride solution. The organic phase was dried over anhydrous magnesium sulfate and evaporated under reduced pressure to remove the solvent to give cyclopropylcarbohydrazide (4.36 g, 44% yield).

References

[1] Patent: WO2005/40142, 2005, A1. Location in patent: Page/Page column 46
[2] Journal of Molecular Structure, 2017, vol. 1146, p. 735 - 743

CYCLOPROPANECARBOXYLIC ACID HYDRAZIDE(6952-93-8)Related Product Information

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• SPECS AG-690/34553016