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DIMETHIRIMOL

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DIMETHIRIMOL Basic information

Product Name:
DIMETHIRIMOL
Synonyms:
  • 'LGC' (1633)
  • DIMETHIRIMOL
  • MILCURB
  • 2-dimethylamino-4-hydroxy-5-n-butyl-6-methylpyrimidine
  • 2-dimethylamino-4-methyl-5-n-butyl-6-hydroxypyrimidine
  • 5-butyl-2-(dimethylamino)-6-methyl-4(1h)-pyrimidinone
  • 5-butyl-2-(dimethylamino)-6-methyl-4-pyrimidinol
  • DiMethiriMol 0
CAS:
5221-53-4
MF:
C11H19N3O
MW:
209.29
EINECS:
226-021-7
Mol File:
5221-53-4.mol
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DIMETHIRIMOL Chemical Properties

Melting point:
103℃
Boiling point:
348.66°C (rough estimate)
Density 
1.0465 (rough estimate)
vapor pressure 
1.5 x 10-3 Pa at 30 °C
refractive index 
1.5700 (estimate)
storage temp. 
0-6°C
pka
5
Water Solubility 
1.2 g l-1 (25 °C)
EPA Substance Registry System
Dimethirimol (5221-53-4)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
21-52
Safety Statements 
36/37
Toxicity
LD50 in female rats (mg/kg): 200-400 i.p., >4000 orally (Elias)
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DIMETHIRIMOL Usage And Synthesis

Uses

Dimethirimol is a systemic fungicide that provides both protective and curative control of powdery mildew (Sphaeratheca fulginea) in cucurbits. Other uses include tobacco, tomatoes and ornamentals.

Uses

Dimethrimolis a fungicide used initially to prevent powdery mildew and other fungal infections or crops. Pesticide.

Uses

Fungicide.

Definition

ChEBI: A member of the class of aminopyrimidines that is 2-dimethylaminopyrimidine carrying methyl, butyl and hydroxy substituents at posiitons 4, 5 and 6 respectively. A fungicide first marketed in 1970, and used particularly in glasshouses to control powdery mi dew, it is no longer approved for use within the European Union.

Metabolic pathway

Information presented in this summary is abstracted from unpublished data in the 1971 ICI dimethirimol petition submitted to the Canadian authority. Dimethirimol is rapidly metabolised in both plants and animals. Primary metabolic reactions in soils, plants and animals are N-dealkylation, hydroxylation of the butyl group and the direct conjugation of dimethirimol in plants (glucosides) and animals (glucuronides). Metabolic pathways are shown in Scheme 1.

Degradation

Dimethirimol (1) is stable to heat and in acid and alkahe solutions. It is decomposed rather rapidly in aqueous solution when exposed to sunlight with an observed DT50 of 7 days.

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