4-IBP Chemical Properties

Melting point:

196-197 °C(Solv: ethyl acetate (141-78-6))

Boiling point:

516.5±50.0 °C(Predicted)

Density 

1.51±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

solubility 

DMSO : 20 mg/mL (47.59 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)

form 

Powder

pka

13.94±0.20(Predicted)

color 

White to off-white

4-IBP Usage And Synthesis

Uses

Pretreatment with 4-IBP, which is a sigma-one receptor (σ1R) agonist, blocked spreading depression (SD).

Definition

ChEBI: 4-iodo-N-[1-(phenylmethyl)-4-piperidinyl]benzamide is a member of piperidines.

Biological Activity

Combines high affinity for σ 1 and moderate affinity for σ 2 sites. Centrally active following systemic administration in vivo .

IC 50

Sigma 1 Receptor; Sigma 2 Receptor