Basic information Safety Supplier Related

CHOLINE CITRATE

Basic information Safety Supplier Related

CHOLINE CITRATE Basic information

Product Name:
CHOLINE CITRATE
Synonyms:
  • CHOLINE CITRATE
  • choline ferric citrate
  • 2-HYDROXYETHYL-TRIMETHYL-AMMONIUM, 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLATE
  • TRICHOLINE CITRATE
  • boxylato(4-))ferrate(1-)
  • ethanaminium,2-hydroxy-n,n,n-trimethyl-,hydroxy(2-hydroxy-1,2,3-propanetricar
  • iron-choline citrate complex
  • Iron Choline Citrate Powder & Soln . 66 % w / w
CAS:
1336-80-7
MF:
C11H21FeNO11
MW:
399.13
EINECS:
215-649-7
Mol File:
1336-80-7.mol
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CHOLINE CITRATE Chemical Properties

Density 
1.574[at 20℃]
vapor pressure 
0Pa at 20℃
Water Solubility 
1084.3g/L at 20℃
LogP
0.3 at 25℃
CAS DataBase Reference
1336-80-7(CAS DataBase Reference)
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Safety Information

WGK Germany 
3

MSDS

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CHOLINE CITRATE Usage And Synthesis

Originator

Ferrolip,Flint,US,1953

Uses

CHOLINE CITRATE is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Manufacturing Process

As described in US Patent 2,575,611, 107 parts of freshly prepared ferric hydroxide are added to 295 parts of choline dihydrogen citrate dissolved in 200 parts of distilled water and heated to approximately 80°C until a homogeneous solution occurs. The resulting reddish brown solution may be used as such or it may be dried by evaporating the water. The dried product is a reddish brown, amorphous solid presenting a glistening surface upon fracture. The dry product is somewhat hygroscopic and is freely soluble in water to give a stable solution. The following paragraph gives an alternative preparation.
One mol of tricholine citrate is dissolved in 6,000 ml of water and two mols of ferric citrate in solid form are added thereto. The reaction mass is then agitated until solution is effected, and until the reaction mass changes from brown to green. Water is removed either under vacuum, or as an azeotrope with benzene or toluene or by heating to a temperature of 110° to 115°C. There is thus obtained a gummy viscous mass which is treated with methanol, about five gallons, whereupon it solidifies, i.e., changes, into a green crystalline compound. Following the treatment with methanol, the mass is filtered and the green compound dried at about 70°C, according to US Patent 2,865,938.

Therapeutic Function

Hematinic

Flammability and Explosibility

Not classified

Safety Profile

Poison by intravenous and intraperitoneal routes. Mildly toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also CHOLINE.

CHOLINE CITRATESupplier

Spectrum Chemical Manufacturing Corp.
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021-021-021-67601398-809-809-809 15221380277
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marketing_china@spectrumchemical.com
Jai Radhe Sales
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+(91)-(79)-26431096/65255722
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info@jairadhesales.com
BOC Sciences
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info@bocsci.com
AFINE CHEMICALS LIMITED
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0571-85134551
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info@afinechem.com
TCI (Shanghai) Chemical Trading Co., Ltd.
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021-61109150
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sales@tcisct.com