Ceramide EOS Chemical Properties

Cosmetics Ingredients Functions

SKIN CONDITIONING
HAIR CONDITIONING

Cosmetic Ingredient Review (CIR)

Ceramide EOS

Ceramide EOS Usage And Synthesis

Description

Ceramide EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid. The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss.