LEUPEPTIN TRIFLUOROACETATE SALT
LEUPEPTIN TRIFLUOROACETATE SALT Basic information
- Product Name:
- LEUPEPTIN TRIFLUOROACETATE SALT
- Synonyms:
-
- LEUPEPTIN TRIFLUOROACETATE SALT
- ACETYL-LEU-LEU-ARG-AL TRIFLUOROACETATE SALT
- LEUPEPTIN TRIFLUOROACETATE FROM*MICROBIA L SOURCE
- leupeptintrifluoroacetatesalt90+%
- Leupeptin trifluoroacetate salt,Acetyl-Leu-Leu-Arg-al trifluoroacetate salt
- Leupeptin trifluoroacetate salt >=90% (HPLC), microbial
- 2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide,2,2,2-trifluoroaceticaci
- CAS:
- 147385-61-3
- MF:
- C22H39F3N6O6
- MW:
- 540.58
- Product Categories:
-
- A to C
- alpha
- Apoptosis Enzymes
- Application Index
- Calpain II
- Calpain II Inhibitors
- Cathepsin B
- Cathepsin H
- Cathepsin/Granzyme Inhibitors &
- Cell Signaling Enzymes
- Coagulation Proteins and Reagents
- D to K
- Endoproteinase Lys-C
- General Inhibitors
- Kallikrein tissue
- Aldehydes
- and Substrates
- Bioactive Small Molecules
- Biochemicals and Reagents
- Building Blocks
- C13-C60
- Calpain
- Carbonyl Compounds
- Cell Biology
- Cell Signaling and Neuroscience
- Chemical Synthesis
- Chymotrypsin
- Core Bioreagents
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- Enzymes
- Inhibitors
- L
- Lys
- Substrates
- inhibitor
- Mol File:
- 147385-61-3.mol
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LEUPEPTIN TRIFLUOROACETATE SALT Chemical Properties
- storage temp.
- -20°C
- solubility
- H2O: 10 mM Solutions are stable only a few hours. Stock solutions are stable up to 6 months at −20°C.
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2925290090
MSDS
- Language:English Provider:SigmaAldrich
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LEUPEPTIN TRIFLUOROACETATE SALT Usage And Synthesis
Uses
Leupeptin Trifluoroacetate is a protease inhibitor, used in the characterization of macroautophagic flux in vivo using leupeptin-based assay.
Biochem/physiol Actions
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
LEUPEPTIN TRIFLUOROACETATE SALTSupplier
Nanjing chengqimei Biotechnology Co., Ltd Gold
- Tel
- 19850819832
- 2173594524@qq.com
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
Guangzhou Isun Pharmaceutical Co., Ltd
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- 020-39119399 18927568969
- isunpharm@qq.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com