Basic information Safety Supplier Related

N-Succinimidyl maleimidoacetate

Basic information Safety Supplier Related

N-Succinimidyl maleimidoacetate Basic information

Product Name:
N-Succinimidyl maleimidoacetate
Synonyms:
  • MALEIMIDOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
  • N-SUCCINIMIDYL MALEIMIDOACETATE
  • a-Maleimidoacetic acid-NHS
  • N-(α-Maleimidoacetoxy)succinimide Ester(AMAS)
  • 1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione
  • N-(α-MaleiMidoacetoxy)succiMide
  • 1H-Pyrrole-2,5-dione, 1-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-
  • MaleiMidoacetic
CAS:
55750-61-3
MF:
C10H8N2O6
MW:
252.18
Product Categories:
  • Nitric Oxide Reagents
  • Cross Linking Reagents
  • Maleimide Derivatives
  • Crosslinking
  • Heterobifunctional Cross-Linking Reagents
  • Protein Modification
  • Cross Linking Reagents,Maleimide Derivatives
  • MTS & Sulfhydryl Active Reagents
Mol File:
55750-61-3.mol
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N-Succinimidyl maleimidoacetate Chemical Properties

Melting point:
174-175°C
Boiling point:
430.1±47.0 °C(Predicted)
Density 
1.63±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
pka
-2.69±0.20(Predicted)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2
InChIKey
TYKASZBHFXBROF-UHFFFAOYSA-N
SMILES
N1(CC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
CAS DataBase Reference
55750-61-3
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29280000

MSDS

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N-Succinimidyl maleimidoacetate Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates.

Uses

A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates.

N-Succinimidyl maleimidoacetateSupplier

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