Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Amide >  N-Chlorosuccinimide

N-Chlorosuccinimide

Basic information Safety Supplier Related

N-Chlorosuccinimide Basic information

Product Name:
N-Chlorosuccinimide
Synonyms:
  • 1-Chloro-2,5-piperidinedione
  • Pyrrolidinedione, 1-chloro-
  • Succinic N-chloroimide
  • succinicn-chloroimide
  • Succinimide, N-chloro-
  • Succinochlorimide
  • N-Chlorosuccini1mide
  • N-ChlorosucciniMide, 98.5%
CAS:
128-09-6
MF:
C4H4ClNO2
MW:
133.53
EINECS:
204-878-8
Product Categories:
  • C-X Bond Formation (Halogen)
  • Chlorination
  • Halogenation
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Succinimides
  • Synthetic Organic Chemistry
  • API intermediates
  • Synthetic Reagents
  • API Intermediate
  • 128-09-6
  • bc0001
Mol File:
128-09-6.mol
More
Less

N-Chlorosuccinimide Chemical Properties

Melting point:
148-150 °C (lit.)
Density 
1,65 g/cm3
vapor pressure 
1.04Pa at 25℃
refractive index 
1.4378 (estimate)
Flash point:
>110°C
storage temp. 
Store at +2°C to +8°C.
solubility 
14g/l
pka
-2.78±0.20(Predicted)
form 
Crystalline Powder
color 
White
Odor
chlorine odor
Water Solubility 
Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.
Sensitive 
Moisture Sensitive
Merck 
14,2164
Boiling point:
216.5°C
BRN 
113915
InChIKey
JRNVZBWKYDBUCA-UHFFFAOYSA-N
LogP
-1.19
CAS DataBase Reference
128-09-6(CAS DataBase Reference)
NIST Chemistry Reference
N-Chlorosuccinimide(128-09-6)
EPA Substance Registry System
N-Chlorosuccinimide (128-09-6)
More
Less

Safety Information

Hazard Codes 
C,Xi
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45-37/39
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
UY1013500
21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
Hazardous Substances Data
128-09-6(Hazardous Substances Data)
Toxicity
MLD orally in rats: 2.7 g/kg (Stohlman, Smith)

MSDS

More
Less

N-Chlorosuccinimide Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.

Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Definition

ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.

Flammability and Explosibility

Non flammable

N-ChlorosuccinimideSupplier

NANJING RUIJIE BIOTECHNOLOGY CO,LTD. Gold
Tel
025-52126580 13776613953
Email
1220449729@qq.com
Nanjing Suruchem CO.,LTD Gold
Tel
025-52406782 18251847779
Email
sales@suruchem.com
Shanghai Ze Chong Pharmaceutical Technology Co., Ltd. Gold
Tel
021-67308028 18621330623
Email
sales@zechongchem.com
Tianjin Nuohan Chemical Co., Ltd. Gold
Tel
166-22132757 13802164402
Email
zhuxuchen2016@yeah.net
Shouguang Jiasheng Chemical Co., Ltd. Gold
Tel
0536-7971999 18232719690
Email
sgjiasheng@hotmail.com