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N-Chlorosuccinimide

Product Name
N-Chlorosuccinimide
CAS No.
128-09-6
Chemical Name
N-Chlorosuccinimide
Synonyms
NCS;NCS;Chlorosuccinimide;N-CHLOROSUCCINAMIDE;N-Chlorosuccinimide (NCS);1-Chloro-2,5-piperidinedione;N-Chlorosuccinimide≥ 99% (Iodometric Titration);NSC 8748;orosuccinimide;APM (Aspartame)
CBNumber
CB7141683
Molecular Formula
C4H4ClNO2
Formula Weight
133.53
MOL File
128-09-6.mol
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N-Chlorosuccinimide Property

Melting point:
148-150 °C (lit.)
Density 
1,65 g/cm3
vapor pressure 
1.04Pa at 25℃
refractive index 
1.4378 (estimate)
Flash point:
>110°C
storage temp. 
Store at +2°C to +8°C.
solubility 
14g/l
pka
-2.78±0.20(Predicted)
form 
Crystalline Powder
color 
White
Odor
chlorine odor
Water Solubility 
Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.
Sensitive 
Moisture Sensitive
Merck 
14,2164
Boiling point:
216.5°C
BRN 
113915
InChIKey
JRNVZBWKYDBUCA-UHFFFAOYSA-N
LogP
-1.19
CAS DataBase Reference
128-09-6(CAS DataBase Reference)
NIST Chemistry Reference
N-Chlorosuccinimide(128-09-6)
EPA Substance Registry System
N-Chlorosuccinimide (128-09-6)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45-37/39
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
UY1013500
F 
21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
Hazardous Substances Data
128-09-6(Hazardous Substances Data)
Toxicity
MLD orally in rats: 2.7 g/kg (Stohlman, Smith)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.02811
Product name
N-Chlorosuccinimide
Purity
for synthesis
Packaging
5G
Price
$38.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02811
Product name
N-Chlorosuccinimide
Purity
for synthesis
Packaging
250g
Price
$88.6
Updated
2024/03/01
Sigma-Aldrich
Product number
109681
Product name
N-Chlorosuccinimide
Purity
98%
Packaging
100g
Price
$33.1
Updated
2024/03/01
Sigma-Aldrich
Product number
109681
Product name
N-Chlorosuccinimide
Purity
98%
Packaging
500g
Price
$104
Updated
2024/03/01
TCI Chemical
Product number
C0291
Product name
N-Chlorosuccinimide
Purity
>98.0%(T)
Packaging
25g
Price
$16
Updated
2024/03/01
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N-Chlorosuccinimide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.

Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Definition

ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.

Flammability and Explosibility

Non flammable

N-Chlorosuccinimide Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Chlorine Succinimide Sodium chlorate hypochlorous acid Succinic acid Ammonia

Preparation Products

5-Amino-2,3-dichloropyridine 5-CHLORO-2'-DEOXYURIDINE 5-Methyl-3-phenylisoxazole-4-carboxylic acid Tau-fluvalinate 2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 3-Chloro-2-hydroxy-5-nitropyridine (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL Cefaclor monohydrate 3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBALDEHYDE 2-Amino-5-chlorobenzonitrile 2-ETHYLCYCLOHEXANONE Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate 2-Chloro-1,4-diaminobenzene 2,3-DICHLORO-5-NITROPYRIDINE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 3-(CHLOROMETHYL)-N,N-DIMETHYLBENZENESULFONAMIDE 2-Chloroquinoline Ketorolac 6-CHLOROQUINAZOLIN-4-AMINE 5-METHYLFURAN-2-BORONIC ACID 4'-BROMO-3'-FLUOROACETANILIDE
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N-Chlorosuccinimide Suppliers

Americas 1 Belgium 1 Canada 1 China 530 Europe 3 Germany 4 India 42 Japan 6 Slovakia 1 South Korea 2 Switzerland 3 Ukraine 1 United Kingdom 11 United States 46 Global 652
NANJING RUIJIE BIOTECHNOLOGY CO,LTD.
Tel
025-52126580 13776613953
Fax
025-52134280
Email
1220449729@qq.com
Country
China
ProdList
6
Advantage
58
Nanjing Suruchem CO.，LTD
Tel
025-52406782 18251847779
Fax
025-52412030
Email
sales@suruchem.com
Country
China
ProdList
7
Advantage
58
Shanghai Ze Chong Pharmaceutical Technology Co., Ltd.
Tel
021-67308028 18621330623
Email
sales@zechongchem.com
Country
China
ProdList
60
Advantage
58
Tianjin Nuohan Chemical Co., Ltd.
Tel
166-22132757 13802164402
Fax
QQ：1732062680
Email
zhuxuchen2016@yeah.net
Country
China
ProdList
74
Advantage
58
Shouguang Jiasheng Chemical Co., Ltd.
Tel
0536-7971999 18232719690
Fax
0536-7971999
Email
sgjiasheng@hotmail.com
Country
China
ProdList
388
Advantage
58
Hubei Nordina Biotechnology Co., Ltd.
Tel
19371278702
Email
n13164103386@163.com
Country
China
ProdList
2928
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8025
Advantage
58
Nanjing Hengweisheng Pharmaceutical Technology Co., Ltd
Tel
19941530336
Email
3991044086@qq.com
Country
China
ProdList
682
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from N-Chlorosuccinimide manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
N-Chlorosuccinimide 128-09-6
Price
US $99.00-80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-21
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
N-Chlorosuccinimide 128-09-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-16
Baoji Guokang Bio-Technology Co., Ltd.
Product
N-Chlorosuccinimide 128-09-6
Price
US $24.00/KG
Min. Order
25KG
Purity
99%
Supply Ability
1000T
Release date
2021-06-04

128-09-6, N-ChlorosuccinimideRelated Search:

Maleimide N-Iodosuccinimide N-Bromosuccinimide Succinimide O-Phthalimide N-Hydroxysuccinimide Bismaleimide N-Methoxy-N-methylacetamide DIALIFOS Difluorochloromethane N-CHLOROSUCCINIMIDE, 98+% N-PROPYLAMINE HYDROCHLORIDE BUTYLAMINE HYDROCHLORIDE Diethylamine hydrochloride DIACETAMIDE chloramide PYRROLIDINEHYDROCHLORIDE N-CHLOROSUCCINIMIDE (67.2.6)

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