2,3-DICHLORO-5-NITROPYRIDINE
Uses- Product Name
- 2,3-DICHLORO-5-NITROPYRIDINE
- CAS No.
- 22353-40-8
- Chemical Name
- 2,3-DICHLORO-5-NITROPYRIDINE
- Synonyms
- 2,3-dichloro-5-nitropyridiMe;2,3-DICHLORO-5-NITROPYRIDINE;Pyridine, 2,3-dichloro-5-nitro-;2,3-Dichloro-5-nitropyridine>2,3-Dichloro-5-nitropyridine 97%;2,3-Dichloro-5-nitropyridine ,97%;2,3-
Dichloro- 5- nitropyridine;2,3-DICHLORO-5-NITROPYRIDINE ISO 9001：2015 REACH - CBNumber
- CB4392086
- Molecular Formula
- C5H2Cl2N2O2
- Formula Weight
- 192.99
- MOL File
- 22353-40-8.mol
2,3-DICHLORO-5-NITROPYRIDINE Property
- Melting point:
- 51-56℃
- Boiling point:
- 256°C(lit.)
- Density
- 1.629±0.06 g/cm3(Predicted)
- Flash point:
- >110°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- -4.99±0.10(Predicted)
- color
- White to Light yellow
- InChI
- InChI=1S/C5H2Cl2N2O2/c6-4-1-3(9(10)11)2-8-5(4)7/h1-2H
- InChIKey
- XLPDVAVQKGDHNO-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C([N+]([O-])=O)C=C1Cl
- CAS DataBase Reference
- 22353-40-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-43-41-37/38-25
- Safety Statements
- 26-36/37/39-45-39
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 1
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 724297
- Product name
- 2,3-Dichloro-5-nitropyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $66.2
- Updated
- 2023/06/20
- Product number
- D4416
- Product name
- 2,3-Dichloro-5-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- D4416
- Product name
- 2,3-Dichloro-5-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $115
- Updated
- 2025/07/31
- Product number
- B426405
- Product name
- 2,3-Dichloro-5-nitropyridine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B426405
- Product name
- 2,3-Dichloro-5-nitropyridine
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
2,3-DICHLORO-5-NITROPYRIDINE Chemical Properties,Usage,Production
Uses
5-Nitro-2,3-Dichloropyridine is an important fine chemical intermediate, widely used in the pharmaceutical and pesticide fields.
Chemical Properties
Light yellow Cryst
Synthesis
22353-38-4
22353-40-8
Quinoline (48.5 mL, 0.41 mol) was slowly added to phosphorous trichloride (164.0 mL, 1.75 mol) at 0 °C and under nitrogen protection. Subsequently, 5-nitro-2-hydroxy-3-chloropyridine (204 mg, 1.17 mmol) was added to this stirred mixture. The reaction mixture was heated to 120 °C and maintained for 2 hours. After completion of the reaction, it was cooled to 0 °C and the reaction was quenched by the addition of ice water. The precipitate was collected by filtration, washed with plenty of water and dried to give 2,3-dichloro-5-nitropyridine. Yield: 220 g (97%). Melting point: 53 °C. 1H NMR (300 MHz, DMSO-d6): δ 9.16 (d, 1H, J = 2.4 Hz), 8.94 (d, 1H, J = 2.4 Hz). 13C NMR (300 MHz, DMSO-d6): δ 158.69, 137.36, 132.51, 130.13, 124.39. mass spectra ( electrospray ionization): m/z 193 ([M+H]+).
References
[1] Synthesis, 1990, # 6, p. 499 - 501
[2] European Journal of Medicinal Chemistry, 2012, vol. 58, p. 355 - 360
[3] Patent: WO2013/117963, 2013, A1. Location in patent: Page/Page column 21
[4] Patent: WO2014/207508, 2014, A1. Location in patent: Page/Page column 55
[5] Roczniki Chemii, 1968, vol. 42, p. 2079,2084
2,3-DICHLORO-5-NITROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,3-DICHLORO-5-NITROPYRIDINE Suppliers
- Tel
- 010-81520996 13439320863
- Fax
- 010-81520996
- hengpugao@126.com
- Country
- China
- ProdList
- 159
- Advantage
- 57
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 0514-87325867
- Fax
- 0086-514-87325867
- sales@siyuchem.com
- Country
- China
- ProdList
- 370
- Advantage
- 55
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 13913622609
- Fax
- 86-512-52893680
- 974295387@qq.com
- Country
- China
- ProdList
- 192
- Advantage
- 61
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
View Lastest Price from 2,3-DICHLORO-5-NITROPYRIDINE manufacturers
- Product
- 2,3-DICHLORO-5-NITROPYRIDINE 22353-40-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-03
- Product
- 2,3-DICHLORO-5-NITROPYRIDINE 22353-40-8
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2,3-DICHLORO-5-NITROPYRIDINE 22353-40-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-02