N-Chlorosuccinimide

Product Name: N-Chlorosuccinimide
CAS No.: 128-09-6
Chemical Name: N-Chlorosuccinimide
Synonyms: NCS;NCS;Chlorosuccinimide;N-CHLOROSUCCINAMIDE;N-Chlorosuccinimide (NCS);1-Chloro-2,5-piperidinedione;N-Chlorosuccinimide≥ 99% (Iodometric Titration);NSC 8748;orosuccinimide;APM (Aspartame)
CBNumber: CB7141683
Molecular Formula: C4H4ClNO2
Formula Weight: 133.53
MOL File: 128-09-6.mol

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N-Chlorosuccinimide Property

Melting point:: 148-150 °C (lit.)
Density: 1,65 g/cm³
vapor pressure: 1.04Pa at 25℃
refractive index: 1.4378 (estimate)
Flash point:: >110°C
storage temp.: Store at +2°C to +8°C.
solubility: 14g/l
pka: -2.78±0.20(Predicted)
form: Crystalline Powder
color: White
Odor: chlorine odor
Water Solubility: Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.
Sensitive: Moisture Sensitive
Merck: 14,2164
Boiling point:: 216.5°C
BRN: 113915
InChIKey: JRNVZBWKYDBUCA-UHFFFAOYSA-N
LogP: -1.19
CAS DataBase Reference: 128-09-6(CAS DataBase Reference)
NIST Chemistry Reference: N-Chlorosuccinimide(128-09-6)
EPA Substance Registry System: N-Chlorosuccinimide (128-09-6)

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Safety

Hazard Codes: C,Xi
Risk Statements: 22-34
Safety Statements: 26-36/37/39-45-37/39
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
RTECS: UY1013500
F: 21
Hazard Note: Irritant
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29251995
Hazardous Substances Data: 128-09-6(Hazardous Substances Data)
Toxicity: MLD orally in rats: 2.7 g/kg (Stohlman, Smith)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.02811
Product name: N-Chlorosuccinimide
Purity: for synthesis
Packaging: 5G
Price: $38.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.02811
Product name: N-Chlorosuccinimide
Purity: for synthesis
Packaging: 250g
Price: $88.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 109681
Product name: N-Chlorosuccinimide
Purity: 98%
Packaging: 100g
Price: $33.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 109681
Product name: N-Chlorosuccinimide
Purity: 98%
Packaging: 500g
Price: $104
Updated: 2024/03/01

TCI Chemical

Product number: C0291
Product name: N-Chlorosuccinimide
Purity: >98.0%(T)
Packaging: 25g
Price: $16
Updated: 2024/03/01

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N-Chlorosuccinimide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.

Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Definition

ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.

Flammability and Explosibility

Non flammable

N-Chlorosuccinimide Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Chlorine Succinimide Sodium chlorate hypochlorous acid Succinic acid Ammonia

Preparation Products

5-Amino-2,3-dichloropyridine 5-CHLORO-2'-DEOXYURIDINE 5-Methyl-3-phenylisoxazole-4-carboxylic acid Tau-fluvalinate 2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 3-Chloro-2-hydroxy-5-nitropyridine (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL Cefaclor monohydrate 3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBALDEHYDE 2-Amino-5-chlorobenzonitrile 2-ETHYLCYCLOHEXANONE Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate 2-Chloro-1,4-diaminobenzene 2,3-DICHLORO-5-NITROPYRIDINE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 3-(CHLOROMETHYL)-N,N-DIMETHYLBENZENESULFONAMIDE 2-Chloroquinoline Ketorolac 6-CHLOROQUINAZOLIN-4-AMINE 5-METHYLFURAN-2-BORONIC ACID 4'-BROMO-3'-FLUOROACETANILIDE

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N-Chlorosuccinimide Suppliers

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View Lastest Price from N-Chlorosuccinimide manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: N-Chlorosuccinimide 128-09-6
Price: US $99.00-80.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-21

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: N-Chlorosuccinimide 128-09-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-16

Baoji Guokang Bio-Technology Co., Ltd.

Product: N-Chlorosuccinimide 128-09-6
Price: US $24.00/KG
Min. Order: 25KG
Purity: 99%
Supply Ability: 1000T
Release date: 2021-06-04

128-09-6, N-ChlorosuccinimideRelated Search:

Maleimide N-Iodosuccinimide N-Bromosuccinimide Succinimide O-Phthalimide N-Hydroxysuccinimide Bismaleimide N-Methoxy-N-methylacetamide DIALIFOS Difluorochloromethane N-CHLOROSUCCINIMIDE, 98+% N-PROPYLAMINE HYDROCHLORIDE BUTYLAMINE HYDROCHLORIDE Diethylamine hydrochloride DIACETAMIDE chloramide PYRROLIDINEHYDROCHLORIDE N-CHLOROSUCCINIMIDE (67.2.6)

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