ChemicalBook > CAS DataBase List > N-Chlorosuccinimide

N-Chlorosuccinimide

Product Name
N-Chlorosuccinimide
CAS No.
128-09-6
Chemical Name
N-Chlorosuccinimide
Synonyms
NCS;NCS;Chlorosuccinimide;N-CHLOROSUCCINAMIDE;N-Chlorosuccinimide (NCS);1-Chloro-2,5-piperidinedione;N-Chlorosuccinimide≥ 99% (Iodometric Titration);NSC 8748;orosuccinimide;APM (Aspartame)
CBNumber
CB7141683
Molecular Formula
C4H4ClNO2
Formula Weight
133.53
MOL File
128-09-6.mol
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N-Chlorosuccinimide Property

Melting point:
148-150 °C (lit.)
Density 
1,65 g/cm3
vapor pressure 
1.04Pa at 25℃
refractive index 
1.4378 (estimate)
Flash point:
>110°C
storage temp. 
Store at +2°C to +8°C.
solubility 
14g/l
pka
-2.78±0.20(Predicted)
form 
Crystalline Powder
color 
White
Odor
chlorine odor
Water Solubility 
Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.
Sensitive 
Moisture Sensitive
Merck 
14,2164
Boiling point:
216.5°C
BRN 
113915
InChIKey
JRNVZBWKYDBUCA-UHFFFAOYSA-N
LogP
-1.19
CAS DataBase Reference
128-09-6(CAS DataBase Reference)
NIST Chemistry Reference
N-Chlorosuccinimide(128-09-6)
EPA Substance Registry System
N-Chlorosuccinimide (128-09-6)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45-37/39
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
UY1013500
F 
21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
Hazardous Substances Data
128-09-6(Hazardous Substances Data)
Toxicity
MLD orally in rats: 2.7 g/kg (Stohlman, Smith)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.02811
Product name
N-Chlorosuccinimide
Purity
for synthesis
Packaging
5G
Price
$38.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02811
Product name
N-Chlorosuccinimide
Purity
for synthesis
Packaging
250g
Price
$88.6
Updated
2024/03/01
Sigma-Aldrich
Product number
109681
Product name
N-Chlorosuccinimide
Purity
98%
Packaging
100g
Price
$33.1
Updated
2024/03/01
Sigma-Aldrich
Product number
109681
Product name
N-Chlorosuccinimide
Purity
98%
Packaging
500g
Price
$104
Updated
2024/03/01
TCI Chemical
Product number
C0291
Product name
N-Chlorosuccinimide
Purity
>98.0%(T)
Packaging
25g
Price
$16
Updated
2024/03/01
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N-Chlorosuccinimide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.

Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Definition

ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.

Flammability and Explosibility

Non flammable

N-Chlorosuccinimide Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Chlorine Succinimide Sodium chlorate hypochlorous acid Succinic acid Ammonia

Preparation Products

5-Amino-2,3-dichloropyridine 5-CHLORO-2'-DEOXYURIDINE 5-Methyl-3-phenylisoxazole-4-carboxylic acid Tau-fluvalinate 2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 3-Chloro-2-hydroxy-5-nitropyridine (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL Cefaclor monohydrate 3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBALDEHYDE 2-Amino-5-chlorobenzonitrile 2-ETHYLCYCLOHEXANONE Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate 2-Chloro-1,4-diaminobenzene 2,3-DICHLORO-5-NITROPYRIDINE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 3-(CHLOROMETHYL)-N,N-DIMETHYLBENZENESULFONAMIDE 2-Chloroquinoline Ketorolac 6-CHLOROQUINAZOLIN-4-AMINE 5-METHYLFURAN-2-BORONIC ACID 4'-BROMO-3'-FLUOROACETANILIDE
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View Lastest Price from N-Chlorosuccinimide manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
N-Chlorosuccinimide 128-09-6
Price
US $99.00-80.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-21
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
N-Chlorosuccinimide 128-09-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-16
Baoji Guokang Bio-Technology Co., Ltd.
Product
N-Chlorosuccinimide 128-09-6
Price
US $24.00/KG
Min. Order
25KG
Purity
99%
Supply Ability
1000T
Release date
2021-06-04

128-09-6, N-ChlorosuccinimideRelated Search:

Maleimide N-Iodosuccinimide N-Bromosuccinimide Succinimide O-Phthalimide N-Hydroxysuccinimide Bismaleimide N-Methoxy-N-methylacetamide DIALIFOS Difluorochloromethane N-CHLOROSUCCINIMIDE, 98+% N-PROPYLAMINE HYDROCHLORIDE BUTYLAMINE HYDROCHLORIDE Diethylamine hydrochloride DIACETAMIDE chloramide PYRROLIDINEHYDROCHLORIDE N-CHLOROSUCCINIMIDE (67.2.6)

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