N-Chlorosuccinimide Property

Melting point:

148-150 °C (lit.)

Density 

1,65 g/cm³

vapor pressure 

1.04Pa at 25℃

refractive index 

1.4378 (estimate)

Flash point:

>110°C

storage temp. 

Store at +2°C to +8°C.

solubility 

14g/l

pka

-2.78±0.20(Predicted)

form 

Crystalline Powder

color 

White

Odor

chlorine odor

Water Solubility 

Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.

Sensitive 

Moisture Sensitive

Merck 

14,2164

Boiling point:

216.5°C

BRN 

113915

InChIKey

JRNVZBWKYDBUCA-UHFFFAOYSA-N

LogP

-1.19

CAS DataBase Reference

128-09-6(CAS DataBase Reference)

NIST Chemistry Reference

N-Chlorosuccinimide(128-09-6)

EPA Substance Registry System

N-Chlorosuccinimide (128-09-6)

Safety

Hazard Codes 

C,Xi

Risk Statements 

22-34

Safety Statements 

26-36/37/39-45-37/39

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

RTECS 

UY1013500

F 

21

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29251995

Hazardous Substances Data

128-09-6(Hazardous Substances Data)

Toxicity

MLD orally in rats: 2.7 g/kg (Stohlman, Smith)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

N-Chlorosuccinimide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.

Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Definition

ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.

Flammability and Explosibility

Non flammable