Basic information Reaction Safety Supplier Related

(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE

Basic information Reaction Safety Supplier Related

(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE Basic information

Product Name:
(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE
Synonyms:
  • (S)-(+)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE
  • (R)-PHANEPHOS
  • (R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE
  • Bisdiphenylphosphinoparacyclophane
  • 4-FLUOROBENZOYLACETONITRILE, 97% N-BOC-4-OXO-L-PROLINE, 97%
  • (s)-phanephos
  • (S)-(+)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane,min.95%(S)-PHANEPHOS
  • (S)-(+)-4,12-BIS-(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE (S)-PHANEPHOS
CAS:
192463-40-4
MF:
C40H34P2
MW:
576.65
Product Categories:
  • Chiral Phosphine
  • PHANEPhos Series
  • organophosphine ligand
Mol File:
192463-40-4.mol
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(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE Chemical Properties

Melting point:
222-225°C
alpha 
+63.2° (c 3.27, CH2Cl2)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
color 
white
optical activity
[α]22/D +34°, c = 1 in chloroform
CAS DataBase Reference
192463-40-4
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-37
Safety Statements 
26-36/37/39
WGK Germany 
3
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(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANE Usage And Synthesis

Reaction

  1. Ligand for rhodium-catalyzed enantioselective hydroboration of cyclopropenes.
  2. Ligand for iridium-catalyzed enantioselective [2+2] cycloaddition of oxabicyclic alkenes with terminal alkynes.
  3. Ligand for the palladium-catalyzed enantioselective hydroxycarbonylation and alkoxycarbonylation of alkenes.
  4. Ligand for the palladium-catalyzed amides synthesis via C(sp3 )–H bond functionalization and CO insertion.
  5. Ligand for iridium-catalyzed diene hydrohydroxymethylation.

Uses

Efficient ligand for asymmetric hydrogentation of dehydroamino acids, methyl esters and keytones.

(R)-(-)-4,12-BIS(DIPHENYLPHOSPHINO)-[2.2]-PARACYCLOPHANESupplier

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