BENSERAZIDE HYDROCHLORIDE Chemical Properties

solubility 

H₂O: 10 mg/mL

form 

solid

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

2

RTECS 

VT9632300

Toxicity

mouse,LD50,intraperitoneal,1700mg/kg (1700mg/kg),Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 62, 1977.

MSDS

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BENSERAZIDE HYDROCHLORIDE Usage And Synthesis

Definition

ChEBI: Benserazide hydrochloride is a hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone. It has a role as an antiparkinson drug, an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor and a dopaminergic agent. It contains a benserazide(1+).

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