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11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE

Basic information Safety Supplier Related

11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE Basic information

Product Name:
11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
Synonyms:
  • 11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
  • AF-DX 116
  • 6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one,5,11-dihydro-11-((2-((diethylamino)m
  • ethyl)-7-piperidinyl)acetyl)-
  • 11-((2-((Diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-(6H)-pyrido[2.3-b][1.4]benzodiazepin-6-one
  • 6H-Pyrido(2,3-B)(1,4)benzodiazepin-6-one, 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-
  • 6H-Pyrido(2,3-B)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((2-((diethylamino)methyl)-7-piperidinyl)acetyl)-
  • Brn 4212983
CAS:
102394-31-0
MF:
C24H31N5O2
MW:
421.54
Product Categories:
  • Acetylcholine receptor
  • Muscarinic
Mol File:
102394-31-0.mol
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11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE Chemical Properties

Boiling point:
573.2±45.0 °C(Predicted)
Density 
1.171
storage temp. 
Store at RT
solubility 
DMSO: soluble5mg/mL (clear solution; warmed)
form 
powder
pka
11.29±0.20(Predicted)
color 
white to beige
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE Usage And Synthesis

Biological Activity

Selective M 2 muscarinic receptor antagonist. K i values are 64, 417, 786, 211 and 5130 nM for human recombinant M 2 , M 1 , M 3 , M 4 and M 5 muscarinic receptors, respectively.

11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONESupplier

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